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[Sar9,Met(O2)11]-Substance P
CAS No. 110880-55-2
[Sar9,Met(O2)11]-Substance P( —— )
Catalog No. M29996 CAS No. 110880-55-2
Sar9, Met (O2)11-Substance P is a neurokinin-1 receptor agonist. It is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout the body, including in the airways of humans and many other species.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 258 | In Stock |
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| 10MG | 465 | In Stock |
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| 25MG | 759 | In Stock |
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| 50MG | 1044 | In Stock |
|
| 100MG | 1413 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
Biological Information
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Product Name[Sar9,Met(O2)11]-Substance P
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NoteResearch use only, not for human use.
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Brief DescriptionSar9, Met (O2)11-Substance P is a neurokinin-1 receptor agonist. It is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout the body, including in the airways of humans and many other species.
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DescriptionSar9, Met (O2)11-Substance P is a neurokinin-1 receptor agonist. It is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout the body, including in the airways of humans and many other species.(In Vitro):[Sar9,Met(O2)11]-Substance P and septide (10-100?pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetNeurokinin Receptor
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RecptorNK1 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number110880-55-2
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Formula Weight1393.66
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Molecular FormulaC64H100N18O15S
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Purity>98% (HPLC)
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SolubilityH2O : 50 mg/mL (35.88 mM; Need ultrasonic)
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SMILES——
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Chemical NameSequence:Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-{Sar}-Leu-Met[O2]-NH2
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127(3):717-28.
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